| 题名 | Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders |
| 年|卷|期 | Journal of Medicinal Chemistry, 60(18), 7677-7702; 2017 |
| 链接 | http://pubs.acs.org/doi/10.1021/acs.jmedchem.7b00807 |
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